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Monday, February 12th, 2018
Table of Contents

1 Introduction
5 PMID
 [F] Diseases Research  / PubMed Research Articles  /
Improvements in health-related quality of life among smokers who quit after hospitalization.

PubMed

 

Resource

Preventive medicine Feb ; ()

Authors

Levy DE1; Chang Y2; Regan S3; Tindle HA4; Singer DE5; Rigotti NA6;

Author Information
  • 1Tobacco Research and Treatment Center at the Massachusetts General Hospital, Boston, MA, United States; Mongan Institute Health Policy Center at the Massachusetts General Hospital, Boston, MA, United States; Department of Medicine, Harvard Medical School, Boston, MA, United States. Electronic address: dlevy3@mgh.harvard.edu.
  • 2Department of Medicine, Harvard Medical School, Boston, MA, United States; Division of General Internal Medicine at the Massachusetts General Hospital, Boston, MA, United States.
  • 3Tobacco Research and Treatment Center at the Massachusetts General Hospital, Boston, MA, United States; Department of Medicine, Harvard Medical School, Boston, MA, United States; Division of General Internal Medicine at the Massachusetts General Hospital, Boston, MA, United States.
  • 4Vanderbilt Center for Tobacco Addiction and Lifestyle, Division of General Internal Medicine, Department of Medicine, Vanderbilt University Medical School, Nashville, TN, United States.
  • 5Department of Medicine, Harvard Medical School, Boston, MA, United States; Division of General Internal Medicine at the Massachusetts General Hospital, Boston, MA, United States.
  • 6Tobacco Research and Treatment Center at the Massachusetts General Hospital, Boston, MA, United States; Mongan Institute Health Policy Center at the Massachusetts General Hospital, Boston, MA, United States; Department of Medicine, Harvard Medical School, Boston, MA, United States; Division of General Internal Medicine at the Massachusetts General Hospital, Boston, MA, United States.

Abstract

Few rigorous longitudinal assessments have examined health-related quality of life (HRQoL) changes after smoking cessation, especially among recently-hospitalized smokers. We compared the change in HRQoL between those who did or did not quit smoking 6 months after hospital discharge. Participants were 1357 smokers recruited for a cessation trial between 2012 and 2014 while hospitalized at two hospitals in Massachusetts and one in Pennsylvania. Cessation was defined as biochemically confirmed 7-day point prevalence abstinence at 6 months or as self-reported continuous abstinence at 1, 3, or 6 months post discharge. HRQoL measures included a single-item global health measure (SF1); the Patient Health Questionnaire for Depression and Anxiety (PHQ-4) screening tool for psychological distress; and the EQ-5D-5L health utilities measure. Multivariable models controlled for age, sex, race, education, insurance, study site, study arm, discharge diagnoses, and baseline HRQoL. Improvements in HRQoL were evident in the first month after discharge among those achieving abstinence compared to continuing smokers. At 6 months post-discharge, those with biochemically confirmed cessation were 30% more likely to report at least good health by the SF1 (aRR 95% CI 1.14-1.45), 19% less likely to screen positive for psychological distress (aRR, 95% CI 0.68-0.93), and had EQ-5D-5L health utility scores 0.05 points (95% CI 0.02-0.08) higher than continuing smokers. Results were similar when assessed as a function of self-reported cessation. Hospital-initiated smoking cessation is associated with rapid statistically and clinically significant improvements in a range of HRQoL measures, providing an additional tool clinicians and health systems could use to encourage smoking cessation.

Copyright © 2017. Published by Elsevier Inc.

PMID

29427673

Others

Publication Type: Journal Article


This article is licensed under the the National Library of Medicine License. It uses material from the PubMed National Library of Medicine Data.


Last Modified:   2016-03-27


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