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[Effects of a lower body weight or waist circumference on cardiovascular risk].




Revista medica de Chile 2017 May 12; 145(5)


Labraña AM1; Durán E2; Martínez MA3; Leiva AM4; Garrido-Méndez A5; Díaz X6; Salas C7; Celis-Morales C8;

Author Information
  • 1Departamento de Nutrición y Dietética, Facultad de Farmacia, Universidad de Concepción, Concepción, Chile.
  • 2Departamento de Nutrición y Dietética, Facultad de Farmacia, Universidad de Concepción, Concepción, Chile.
  • 3Instituto de Farmacia, Facultad de Ciencias, Universidad Austral de Chile, Valdivia, Chile.
  • 4Instituto de Anatomía, Histología y Patología, Facultad de Medicina, Universidad Austral de Chile, Valdivia, Chile.
  • 5Departamento de Educación Física, Universidad San Sebastián, Concepción, Chile.
  • 6Universidad del Biobío, Chillán, Chile.
  • 7Departamento de Educación Física, Facultad de Educación, Universidad de Concepción, Concepción, Chile.
  • 8Human Nutrition Research Centre, Institute of Cellular Medicine, University of Newcastle, Newcastle upon Tyne, United Kingdom.


BACKGROUND: Overall and central obesity are important risk factors for cardiovascular disease.

AIM: To investigate the association of body weight, body mass index (BMI) and waist circumference (WC) with cardiovascular risk factors in Chile.

MATERIAL AND METHODS: We included 5,157 participants from the National Health Survey 2009-2010. Prevalence of type 2 diabetes, hypertension, metabolic syndrome and dyslipidemia (high total cholesterol and triglyceride levels and low HDL-cholesterol) were defined using international recommendations. BMI and WC were measured using standardized protocols.

RESULTS: A five percent lower body weight, BMI and WC were associated with a significant reduction in cardiovascular risk factors. For each 5% reduction in body weight, the risk for hypertension decreased by 8 and 9% in women and men respectively. Similar risk reductions were observed for diabetes (9 and 11% respectively), metabolic syndrome (23 and 30% respectively), low HDL cholesterol (13 and 13% respectively), high triglyceride levels (16 and 18% respectively) and total cholesterol (8 and 10% respectively). Similar findings were observed for BMI and WC.

CONCLUSIONS: Lower body weight, BMI or WC are associated with important reductions in cardiovascular risk factors. A 5% reduction in these adiposity markers could be a perfectly feasible goal for lifestyle interventions.




Publication Type: English Abstract, Journal Article

This article is licensed under the the National Library of Medicine License. It uses material from the PubMed National Library of Medicine Data.

Last Modified:   2016-03-27

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