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Tuesday, June 27th, 2017
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 [F] Diseases Research  / PubMed Research Articles  /
Nanotechnologies for In Vitro IgE Testing.




Current allergy and asthma reports 2017 Jul 17; 17(7)


Märki I1; Rebeaud F2;

Author Information
  • 1Abionic SA, Biopôle, sect. Esplanade SE-A, Route de la Corniche 3, CH-1066, Epalinges, Switzerland. iwan.maerki@abionic.com.
  • 2Abionic SA, Biopôle, sect. Esplanade SE-A, Route de la Corniche 3, CH-1066, Epalinges, Switzerland.


PURPOSE OF REVIEW: This review discusses the recent advances in the development of IgE antibody assays based on nanotechnologies. IgE blood testing is an important part of the diagnostic workup of IgE-mediated hypersentivity. We also address the challenges in moving from an academic proof-of-concept to a product routinely used by allergy experts.

RECENT FINDINGS: Several nanotechnologies have been applied to the field of IgE testing: nanoparticles are used either as a support to capture analytes or as a detection tool to enhance the measurement signal. Nanofluidics allows to reduce assay time by enhancing molecular interaction. Nanotechnologies bring forth new methods for in vitro IgE testing. Substantial advantages such as lower sample volume, shorter assay time, simplified procedures, and lower analytic sensitivity, without affecting test precision and accuracy, can be achieved thanks to nanotechnologies.




Publication Type: Journal Article, Review

This article is licensed under the the National Library of Medicine License. It uses material from the PubMed National Library of Medicine Data.

Last Modified:   2016-03-27

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