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Tuesday, June 27th, 2017
Table of Contents

1 Introduction
5 PMID
 [F] Diseases Research  / PubMed Research Articles  /
The impact of breast cancer treatments on sleep quality 1 year after cancer diagnosis.

PubMed

 

Resource

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2017 Jun 17; ()

Authors

Fontes F1; Pereira S2; Costa AR3; Gonçalves M4; Lunet N5;

Author Information
  • 1ISPUP-EPIUnit, University of Porto, Rua das Taipas, 135, 4050-600, Porto, Portugal.
  • 2ISPUP-EPIUnit, University of Porto, Rua das Taipas, 135, 4050-600, Porto, Portugal.
  • 3ISPUP-EPIUnit, University of Porto, Rua das Taipas, 135, 4050-600, Porto, Portugal.
  • 4ISPUP-EPIUnit, University of Porto, Rua das Taipas, 135, 4050-600, Porto, Portugal.
  • 5ISPUP-EPIUnit, University of Porto, Rua das Taipas, 135, 4050-600, Porto, Portugal. nlunet@med.up.pt.

Abstract

PURPOSE: The increasing number of women living longer with potential side effects of breast cancer treatment highlights the need of a comprehensive assessment of its burden. Therefore, we aimed to quantify the relation between different breast cancer treatments and sleep quality 1 year after diagnosis.

METHODS: A cohort of 502 newly diagnosed breast cancer patients was prospectively followed. Sleep quality was evaluated with the Pittsburgh Sleep Quality Index (PSQI), at baseline and at the 1-year follow-up. Odds ratios (OR) were computed to quantify the association between patient characteristics and poor sleep quality (PSQI score >5) at baseline, and relative risks (RR) were computed for the association between treatments and the occurrence of poor sleep quality at 1 year.

RESULTS: A total of 60.2% of the patients had poor sleep quality before breast cancer treatments, especially those with anxiety [OR = 2.86, 95% confidence interval (95%CI) 1.92 to 4.27] or depression (OR = 5.25, 95%CI 2.01 to 13.67). Radiotherapy increased the risk of poor sleep quality at 1 year (RR = 3.71, 95%CI 1.15 to 11.96, for a cumulative dose >50 Gy) and there was a tendency for a higher risk in those submitted to chemotherapy, although not statistically significant.

CONCLUSIONS: Our study shows that sleep disturbances are frequent before cancer treatment and confirms their co-occurrence with other medical conditions, such as anxiety and depression. Different breast cancer treatments increase the risk of impaired sleep quality, therefore contributing to the global disability associated with cancer treatments.



PMID

28623402

Others

Publication Type: Journal Article


This article is licensed under the the National Library of Medicine License. It uses material from the PubMed National Library of Medicine Data.


Last Modified:   2016-03-27


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